Science

Novel autoantibody associated with Hodgkin’s lymphoma

Autoantibodies targeting the protein RGS8 (regulator of G-protein signaling 8) are associated with a particular subtype of Hodgkin’s lymphoma, as described in a recently published study performed in a collaboration between EUROIMMUN and research institutes in France, Spain and USA. The novel autoantibodies are suggested to be of at least intermediate risk for paraneoplastic neurological […]

Science

Novel cell-based assay for autoantibody detection in demyelination

A novel cell-based immunofluorescence assay (CBA) provides sensitive and specific detection of IgM antibodies against myelin-associated glycoprotein (MAG), as demonstrated in a study published in collaboration with scientists from the University of Verona and the Pediatric Research Institute in Padua, Italy. The Anti-MAG CBA is now available for research use*. Anti-MAG-IgM antibodies are markers for

Science

Novel autoantibody against septin-3 discovered in neurological disease

The cytoskeleton protein septin-3 has been identified as a novel target antigen of autoantibodies in patients with paraneoplastic cerebellar ataxia. The new biomarker was discovered in a collaborative study between scientists at EUROIMMUN, the University of Heidelberg and further clinics in Germany. Septins are cytoskeletal proteins with multiple roles in cell division, cellular polarisation, morphogenesis

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