The new EUROIMMUN ELISA for detection of soluble CD163 (sCD163) in urine is now available. This is the first CE-certified test for this parameter on the market. Mark Little, Professor for nephrology at the Trinity College in Dublin (Ireland) showed in a study that increased concentrations of sCD163 in urine indicate an inflammation of the […]
G-protein-coupled receptors (GPCR) are transmembrane proteins involved in various physiological and pathophysiological processes and signalling pathways. Due to their key role, they have been in the focus of science and industry for the past decades to search for new diagnostic markers and pharmaceuticals for the treatment of various diseases. Already around 30% of the therapeutic
In December 2017, the German Society for Rheumatology (DGRh) published their first guideline for the diagnosis and treatment of ANCA-associated forms of vasculitis (AAV) [1]. The AAV encompass granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss syndrome), which all occur with autoantibodies against cytoplasmic antigens
