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Omicron-induced T- and B-cell immunity in vaccinated and naïve individuals

A recent study has demonstrated substantial differences in SARS-CoV-2 immunity after Omicron infection in triple-COVID-19-vaccinated and antigen-naïve individuals, which may influence cross-protection against future variants. The study was performed as part of a collaboration between the Hannover Medical School, Germany and EUROIMMUN. Omicron variants are B-cell immune escape variants of SARS-CoV-2 that elude the defence […]

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Computer-aided classification of IIF patterns in autoimmune dermatoses

Deep neural networks incorporating segmentation provide highly accurate classification of immunofluorescence patterns on the tissue substrates esophagus and salt-split skin for detection of autoimmune bullous dermatoses (AIBD). A recently published study in collaboration with researchers at the Department of Dermatology and Lübeck Institute of Experimental Dermatology of the University of Lübeck, Germany describes the development

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Recombinant ELISAs increase efficiency of CMV serodiagnosis in pregnant women

EUROIMMUN ELISAs based on recombinant antigens p52 (IgM) and glycoprotein B (IgG) from cytomegalovirus (CMV) provided a higher rate of conclusive results in first-line testing of samples from pregnant women than lysate-based assays. A recombinant testing strategy could thus help to reduce the number of analyses required for routine CMV screening during pregnancy. These are

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Reliable detection of anti-CCHFV antibodies in acute infections

EUROIMMUN ELISAs for detection of antibodies against Crimean-Congo haemorrhagic fever virus (CCHFV) reliably identify acute CCHF cases and are suitable for laboratories involved in on-site outbreak support. This was demonstrated in a recently published study in collaboration with scientists at a national reference laboratory in Turkey. Crimean-Congo haemorrhagic fever (CCHF) is a life-threatening tick-borne disease

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