The cytoskeleton protein septin-3 has been identified as a novel target antigen of autoantibodies in patients with paraneoplastic cerebellar ataxia. The new biomarker was discovered in a collaborative study between scientists at EUROIMMUN, the University of Heidelberg and further clinics in Germany. Septins are cytoskeletal proteins with multiple roles in cell division, cellular polarisation, morphogenesis […]

Deep neural networks incorporating segmentation provide highly accurate classification of immunofluorescence patterns on the tissue substrates esophagus and salt-split skin for detection of autoimmune bullous dermatoses (AIBD). A recently published study in collaboration with researchers at the Department of Dermatology and Lübeck Institute of Experimental Dermatology of the University of Lübeck, Germany describes the development

Microscopy is a fundamental tool in biomedical research and clinical diagnostics. However, each laboratory has different requirements for its instruments: While laboratories with a low sample throughput tend to use manual microscopes, for example for the evaluation of indirect immunofluorescence tests, large laboratories with a high throughput and a broad diagnostic spectrum rather benefit from

EUROIMMUN ELISAs based on recombinant antigens p52 (IgM) and glycoprotein B (IgG) from cytomegalovirus (CMV) provided a higher rate of conclusive results in first-line testing of samples from pregnant women than lysate-based assays. A recombinant testing strategy could thus help to reduce the number of analyses required for routine CMV screening during pregnancy. These are

EUROIMMUN ELISAs for detection of antibodies against Crimean-Congo haemorrhagic fever virus (CCHFV) reliably identify acute CCHF cases and are suitable for laboratories involved in on-site outbreak support. This was demonstrated in a recently published study in collaboration with scientists at a national reference laboratory in Turkey. Crimean-Congo haemorrhagic fever (CCHF) is a life-threatening tick-borne disease