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Cross-reactive anti-CCD antibodies can hinder allergy diagnostics

In persons with type I allergies, the immune system forms IgE antibodies at first contact with a usually harmless substance (allergen) from the environment, e.g. against certain proteins in pollen, animal hair or food. At every further contact, the binding between the antibodies and the allergen can cause diverse immune reactions, including swelling of mucous […]

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Advantages of the modern allergy diagnostics

In the current issue of the medical journal Trillium Diagnostik (14(3): 172-173), Prof Dr Rudolf Gruber and Dr Gabriele Egert, experts for laboratory diagnostics, clearly explain the advantages of defined recombinant allergen components which are applied in modern molecular allergy diagnostics. While allergens which are extracted and purified from natural allergen sources always constitute a

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Peanut allergy: same but different

Two children, Lisa and Tom, are tested for different food allergies with a skin test by an allergist at the same day, since both children complain about various symptoms such as oral prickling, rashes and nausea. In both cases, the allergy test indicates an obvious immune reaction against peanut extract – a diagnostic agent which

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Novel test for differentiation of “true“ peanut allergies and unproblematic cross reactions

Peanut allergies belong to the most frequent food allergies which already establish during infancy. Contact with the allergen often causes severe systemic reactions of the organism including circulatory collapse (anaphylaxis). The diagnosis of a peanut allergy mostly implies serious restrictions of the patient’s life quality, especially with respect to the diet, since every contact with

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